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Compound category: Benzenoids
(total 18 related compounds in database, current show from 1 to 10)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase
Fluorothiazinon Depiction based on curated SMILES OH O S F F H 3 C NH O N N O Acinetobacter
Chlamydia
Klebsiella
Pseudomonas
Salmonella		 Biofilm
TTSS (Type III secretion system)
Biofilm
TTSS (Type III secretion system)
TTSS (SPI-1 encode); TTSS (SPI-2 encode)		 In vivo
In vivo
In vitro
In vivo
Phase II trial
4-chloro-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide Depiction based on curated SMILES Cl O OH N N H Chlamydia
Salmonella
Shigella		 TTSS (Type III secretion system)
TTSS (SPI-1 encode); TTSS (SPI-2 encode)
TTSS (Type III secretion system)		 In vitro
In vitro
In vitro
4-[(3-ethoxy-2-hydroxyphenyl)methyl]-N-(4-fluorophenyl)-5-oxo-1,3,4-thiadiazine-2-carboxamide Depiction based on curated SMILES O S F H 3 C NH O N N OH O Chlamydia TTSS (Type III secretion system) In vitro
N'-(2-Hydroxy-3,5-dibromobenzylidene)-4-nitrobenzhydrazide Depiction based on curated SMILES Br _ O O + N OH O Br N HN Chlamydia TTSS (Type III secretion system) In vitro
N-[(E)-(3-fluoro-2-hydroxyphenyl)methylideneamino]-4-nitrobenzamide Depiction based on curated SMILES _ O O + N OH O F N N H Chlamydia TTSS (Type III secretion system) In vitro
N'-[(E)-(5-bromo-2-hydroxyphenyl)methylidene]-2-phenylacetohydrazide Depiction based on curated SMILES N OH Br O N H Chlamydia TTSS (Type III secretion system) In vitro
(E)-N'-(5-Bromo-2-hydroxybenzylidene)-3-methoxybenzohydrazide Depiction based on curated SMILES OH Br H 3 C N N H O O Chlamydia TTSS (Type III secretion system) In vitro
N-[(E)-(5-tert-butyl-2-hydroxyphenyl)methylideneamino]-4-methylbenzamide Depiction based on curated SMILES OH CH 3 H 3 C H 3 C CH 3 N N H O Chlamydia TTSS (Type III secretion system) In vitro
Compound 17
(internal name in literature)		 Depiction based on curated SMILES O S F F F CH 3 HN O N N OH O Chlamydia TTSS (Type III secretion system) In vitro
Compound 18
(internal name in literature)		 Depiction based on curated SMILES N S O OH Br N O F F F N H Chlamydia TTSS (Type III secretion system) In vitro
   


NOTE: for more interactive and statistic charts, please visit the JavaScript-rich interface of VFDB.



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