GenomeComp is a tool for summarizing, parsing and visualizing the genome wide sequence comparison results derived from voluminous BLAST textual output, so as to locate the rearrangements, insertions or deletions of genome segments between species or strains.
It can be easily used to compare, parsing and visualize large genomic sequences, especially closely related genomes such as inter-species or inter-strains. In addition, it can also show other sequence features like repeat sequence distributions in one whole-genome DNA sequence by comparing the genome to itself.
It is a stand-alone graphical user interface (GUI) program which runs on Linux, Unix, Mac OS X (tested on version 10.2.4 only) and Microsoft Windows platforms and is written in Perl/Tk.
Releases (Last update: )
New: The second release of GenomeComp is available as following:
The first release of GenomeComp is available in two distribution formats as following:
The user manual explains how to install and run GenomeComp and the major parts of the program does. The HTML files for the manual are also available as a compressed UNIX tar file or a windows Zip file.
When you have comments about the manual please send them to the GenomeComp developers.
GenomeComp has been efficiently applied in comparison between different Shigella genomes (average genome size 4.6 Mbp) as well as against its close relatives, such as the non-pathogenic K-12 strain MG1655 (genome size 4.6 Mbp) and enterohemorrhagic O157:H7 strain EDL933 (genome size 5.5 Mbp) of Escherichia coli for the Shigella genome project in our center. See the following publications for more detail information about this.
The development of GenomeComp was funded by Chinese Academy of Sciences Grant No. KSCX2-2-07.
Since May-19-2003, there have been visits.
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