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Genome maps
S. dysenteriae Sd197
S. flexneri Sf301
S. boydii Sb227
S. sonnei Ss046

General features
Linear alignment
Orthologs order
Metabolic pathway
Virulence factors
CGH results

Analysis tools
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BLAST search
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VFDB database

Metabolic pathways in Shigella


    1. Metabolism
      Carbohydrate   Energy   Lipid   Nucleotide   Amino acid   Other amino acid
      Glycan   PK/NRP   Cofactor/vitamin   Secondary metabolite   Xenobiotics
    2. Genetic Information Processing
    3. Cellular Processes

1. Carbohydrate Metabolism
Glycolysis / Gluconeogenesis
Citrate cycle (TCA cycle)
Pentose phosphate pathway
Pentose and glucuronate interconversions
Fructose and mannose metabolism
Galactose metabolism
Ascorbate and aldarate metabolism
Starch and sucrose metabolism
Aminosugars metabolism
Nucleotide sugars metabolism
Pyruvate metabolism
Glyoxylate and dicarboxylate metabolism
Propanoate metabolism
Butanoate metabolism
C5-Branched dibasic acid metabolism
Inositol phosphate metabolism
2. Energy Metabolism
Oxidative phosphorylation
ATP synthesis
Carbon fixation
Reductive carboxylate cycle (CO2 fixation)
Methane metabolism
Nitrogen metabolism
Sulfur metabolism
3. Lipid Metabolism
Fatty acid biosynthesis (path 1)
Fatty acid biosynthesis (path 2)
Fatty acid metabolism
Biosynthesis of steroids
Bile acid biosynthesis
Androgen and estrogen metabolism
Glycerolipid metabolism
Glycerophospholipid metabolism
Prostaglandin and leukotriene metabolism
4. Nucleotide Metabolism
Purine metabolism
Pyrimidine metabolism
5. Amino Acid Metabolism
Glutamate metabolism
Alanine and aspartate metabolism
Glycine, serine and threonine metabolism
Methionine metabolism
Cysteine metabolism
Valine, leucine and isoleucine degradation
Valine, leucine and isoleucine biosynthesis
Lysine biosynthesis
Lysine degradation
Arginine and proline metabolism
Histidine metabolism
Tyrosine metabolism
Phenylalanine metabolism
Tryptophan metabolism
Phenylalanine, tyrosine and tryptophan biosynthesis
Urea cycle and metabolism of amino groups
6. Metabolism of Other Amino Acids
beta-Alanine metabolism
Taurine and hypotaurine metabolism
Aminophosphonate metabolism
Selenoamino acid metabolism
Cyanoamino acid metabolism
D-Glutamine and D-glutamate metabolism
D-Alanine metabolism
Glutathione metabolism
7. Glycan Biosynthesis and Metabolism
N-Glycan biosynthesis
N-Glycan degradation
O-Glycan biosynthesis
Glycosaminoglycan degradation
Lipopolysaccharide biosynthesis
Peptidoglycan biosynthesis
Glycosphingolipid metabolism
Blood group glycolipid biosynthesis-neolactoseries
Globoside metabolism
Ganglioside biosynthesis
8. Biosynthesis of Polyketides and Nonribosomal Peptides
Biosynthesis of ansamycins
Polyketide sugar unit biosynthesis
Biosynthesis of siderophore group nonribosomal peptides
9. Metabolism of Cofactors and Vitamins
Thiamine metabolism
Riboflavin metabolism
Vitamin B6 metabolism
Nicotinate and nicotinamide metabolism
Pantothenate and CoA biosynthesis
Biotin metabolism
Folate biosynthesis
One carbon pool by folate
Porphyrin and chlorophyll metabolism
Ubiquinone biosynthesis
10. Biosynthesis of Secondary Metabolites
Terpenoid biosynthesis
Limonene and pinene degradation
Alkaloid biosynthesis I
Alkaloid biosynthesis II
Streptomycin biosynthesis
Novobiocin biosynthesis
11. Biodegradation of Xenobiotics
Caprolactam degradation
Biphenyl degradation
Toluene and xylene degradation
gamma-Hexachlorocyclohexane degradation
Tetrachloroethene degradation
Styrene degradation
1,4-Dichlorobenzene degradation
Nitrobenzene degradation
Ethylbenzene degradation
Fluorene degradation
Carbazole degradation
Benzoate degradation via CoA ligation
Benzoate degradation via hydroxylation
Bisphenol A degradation
1- and 2-Methylnaphthalene degradation

Genetic Information Processing
1. Transcription
RNA polymerase
2. Translation
Aminoacyl-tRNA biosynthesis
3. Folding, Sorting and Degradation
Protein export
Type II secretion system
Type III secretion system
4. Replication and Repair
DNA polymerase

Cellular Processes
1. Cell Motility
Bacterial chemotaxis
Flagellar assembly
Note: all metabolic pathway information and map figures are available from KEGG.

Copyright © 2005 State Key Laboratory for Molecular Virology and Genetic Engineering, Beijing, China