|
Shionone |
|
Streptococcus |
Pneumolysin |
Preclinical (in vivo) |
Du R, et al. 2022. Molecules |
|
Linalool |
Depiction based on curated SMILES
CH
3
H
3
C
CH
2
OH
CH
3
|
Streptococcus |
Biofilm |
Preclinical (in vivo) |
Praseetha S, et al. 2023. Antibiotics (Basel) |
|
N-Dodecyl-4-(2-amino-1H-imidazole-4-yl)butanamide |
Depiction based on curated SMILES
N
H
N
H
2
N
N
H
O
CH
3
|
Streptococcus |
Biofilm |
Preclinical (in vivo) |
Liu C, et al. 2023. mBio |
|
4-(2-amino-1H-imidazol-5-yl)-N-hexadecylbutanamide |
Depiction based on curated SMILES
N
H
2
N
N
H
O
N
H
CH
3
|
Streptococcus |
Biofilm |
Preclinical (in vivo) |
Liu C, et al. 2023. mBio |
|
4-(2-amino-1H-imidazol-5-yl)-N-octadecylbutanamide |
Depiction based on curated SMILES
N
H
2
N
N
H
O
N
H
CH
3
|
Streptococcus |
Biofilm |
Preclinical (in vivo) |
Liu C, et al. 2023. mBio |
|
4-(2-amino-1H-imidazol-5-yl)-N-tetradecylbutanamide |
Depiction based on curated SMILES
N
H
2
N
N
H
O
N
H
CH
3
|
Streptococcus |
Biofilm |
Preclinical (in vivo) |
Liu C, et al. 2023. mBio |
|
N-Tridecyl-2-amino-1H-imidazole-4-butyramide |
Depiction based on curated SMILES
N
NH
2
HN
O
N
H
H
3
C
|
Acinetobacter Streptococcus |
BfmRS Biofilm |
Preclinical (in vitro) Preclinical (in vivo) |
Thompson RJ, et al. 2012. Biochemistry Liu C, et al. 2023. mBio |
|
4-(2-amino-1H-imidazol-5-yl)-N-undecylbutanamide |
Depiction based on curated SMILES
N
H
N
NH
2
HN
O
H
3
C
|
Streptococcus |
Biofilm |
Preclinical (in vivo) |
Liu C, et al. 2023. mBio |
|
Fascioquinol E |
Depiction based on curated SMILES
H
3
C
H
3
C
H
3
C
H
3
C
HO
OH
O
O
S
O
H
3
C
|
Streptococcus |
Immune modulation |
Preclinical (in vivo) |
Standish AJ, et al. 2012. PLoS One |
|
16-Oxocleroda-3,13E-dien-15-oic acid |
Depiction based on curated SMILES
CH
3
CH
3
O
OH
O
CH
3
CH
3
H
H
|
Streptococcus |
Biofilm |
Preclinical (in vitro) |
Khan AK, et al. 2017. Eur J Med Chem |
|
| | |