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Compound category: Pyridoindoles
(total 12 related compounds in database, current show from 1 to 10)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase
Norharmane Depiction based on curated SMILES N H N Escherichia
Pseudomonas
Biofilm
Biofilm
In vivo
In vitro
(4S)-2-Chloro-4beta-(4-bromophenyl)-12-[[2-(methylthio)-3-pyridyl]carbonyl]-3,4,6,7,12,12balpha-hexahydroindolo[2,3-a]quinolizine-6alpha-carboxylic acid Depiction based on curated SMILES N N O S CH 3 Cl H H Br N O HO Mycobacterium Exoenzyme In vitro
methyl (1S,12S)-16-[(2-hydroxyphenyl)methyl]-13-oxo-3,16-diazatetracyclo[10.3.1.02,10.04,9]hexadeca-2(10),4,6,8-tetraene-14-carboxylate Depiction based on curated SMILES N HN OH CH 3 O H H O O Mycobacterium Exoenzyme In vitro
methyl (1S,12S)-16-[(3,4-dichlorophenyl)methyl]-13-oxo-3,16-diazatetracyclo[10.3.1.02,10.04,9]hexadeca-2(10),4,6,8-tetraene-14-carboxylate Depiction based on curated SMILES HN Cl Cl CH 3 N O H H O O Mycobacterium Exoenzyme In vitro
methyl (1S,12S)-16-[(3-bromo-4-fluorophenyl)methyl]-13-oxo-3,16-diazatetracyclo[10.3.1.02,10.04,9]hexadeca-2(10),4,6,8-tetraene-14-carboxylate Depiction based on curated SMILES HN Br F CH 3 N O H H O O Mycobacterium Exoenzyme In vitro
methyl (1S,12S)-16-[(3-hydroxyphenyl)methyl]-13-oxo-3,16-diazatetracyclo[10.3.1.02,10.04,9]hexadeca-2(10),4,6,8-tetraene-14-carboxylate Depiction based on curated SMILES N HN HO CH 3 O H H O O Mycobacterium Exoenzyme In vitro
methyl (1S,12S)-16-[(4,6-dichloro-2H-chromen-3-yl)methyl]-13-oxo-3,16-diazatetracyclo[10.3.1.02,10.04,9]hexadeca-2(10),4,6,8-tetraene-14-carboxylate Depiction based on curated SMILES Cl O Cl N H O O H CH 3 H O N Mycobacterium Exoenzyme In vitro
methyl (1S,12S)-16-[(4-chloro-6-fluoro-2H-chromen-3-yl)methyl]-13-oxo-3,16-diazatetracyclo[10.3.1.02,10.04,9]hexadeca-2(10),4,6,8-tetraene-14-carboxylate Depiction based on curated SMILES F O Cl N H O O H CH 3 H O N Mycobacterium Exoenzyme In vitro
methyl (1S,12S)-16-[(5-chloro-1H-indol-3-yl)methyl]-13-oxo-3,16-diazatetracyclo[10.3.1.02,10.04,9]hexadeca-2(10),4,6,8-tetraene-14-carboxylate Depiction based on curated SMILES Cl N H N H O O H CH 3 H O N Mycobacterium Exoenzyme In vitro
methyl (1S,12S)-16-[(5-methylfuran-2-yl)methyl]-13-oxo-3,16-diazatetracyclo[10.3.1.02,10.04,9]hexadeca-2(10),4,6,8-tetraene-14-carboxylate Depiction based on curated SMILES H CH 3 O O NH CH 3 O H N O Mycobacterium Exoenzyme In vitro
   


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