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N'-[(E)-(3-ethoxy-2-hydroxyphenyl)methylideneamino]oxamide

Drug details:
Molecular formula: C11H13N3O4

Classification: Amino acids, peptides, and analogues; Carboxylic acids and derivatives; Organic acids and derivatives; Organic compounds;
Chemical structure:
Depiction based on curated SMILES N OH O NH 2 O NH H 3 C O

Evidence for compound's anti-virulence activity:

Salmonella
Related VF: TTSS (SPI-1 encode); TTSS (SPI-2 encode)
Target: Not determined
Drug effect: Efficiently affected SPI1 and SPI2 activity.
Max phase: Preclinical (in vitro)
Publication:
Negrea A, et al., 2007. Salicylidene acylhydrazides that affect type III protein secretion in Salmonella enterica serovar typhimurium. Antimicrob Agents Chemother 51(8):2867-76.








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