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N-methyl-3-(1-(4-(piperazin-1-yl)phenyl)-5-(4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)-1H-pyrazol-3-yl)propanamide

Drug details:
Molecular formula: C30H30F3N5O

Classification: Piperazines; Diazinanes; Organoheterocyclic compounds; Organic compounds;
Synonyms:  OSU-T315 (1,5-regioisomer)
compound 22 [PMID: 21823616]
N-methyl-3-[1-(4-piperazin-1-ylphenyl)-5-[4-[4-(trifluoromethyl)phenyl]phenyl]pyrazol-3-yl]propanamide
ILK inhibitor 22(1,5)

Chemical structure:
Depiction based on curated SMILES F F F N H O N N CH 3 N N H

Acinetobacter
Related VFcategory: Biofilm
Target: WrbA
Drug effect: Inhibits WrbA to reduce capacity to transition to a biofilm-forming lifestyle.
Max phase: In vitro
Publication:
Moshiri J, et al., 2018. Identification of a Small Molecule Anti-biofilm Agent Against Salmonella enterica. Front Microbiol 9:2804.

Salmonella
Related VFcategory: Biofilm
Target: WrbA
Drug effect: Inhibits biofilm formation.
Max phase: In vitro
Publication:
Moshiri J, et al., 2018. Identification of a Small Molecule Anti-biofilm Agent Against Salmonella enterica. Front Microbiol 9:2804.








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