Drug details:
Molecular formula: C₄H₄O₂

Standard name: 3H-furan-2-one

Synonyms:

2(3H)-Furanone furan-2(3H)-one 3H-furan-2-one .alpha.-Crotonolactone 2-furanone 2-Oxo-2,3-dihydrofuran alpha-Crotonolactone but-3-en-4-olide alpha-Furanone ......

Curated SMILES: C1C=COC1=O

Acinetobacter
Related VFcategory: Biofilm
Target: Not determined
Drug effect: Inhibits the biofilms formation of bacterial by replacing the binding sites of quorum sensing signal molecules.
Max phase: In vitro
Publication:
Peng Q, et al., 2020. In vitro activity of biofilm inhibitors in combination with antibacterial drugs against extensively drug-resistant Acinetobacter baumannii. Sci Rep 10(1):18097.