Drug details:
Molecular formula: C₂₀H₁₃FN₄O₄

Standard name: 4-fluoro-N-[4-(1-hydroxy-6-nitrobenzimidazol-2-yl)phenyl]benzamide

Curated SMILES: O=C(NC1=CC=C(C2=NC3=CC=C([N+](=O)[O-])C=C3N2O)C=C1)C1=CC=C(F)C=C1

Pseudomonas
Related VF: TTSS (Type III secretion system)
Target: ExsA
Drug effect: Inhibits DNA binding by interacting specifically with the DNA-binding domain of ExsA and its homologs AscA, LscA, LcrF, ExsAvp (from Vibrio parahaemolyticus).
Max phase: In vitro
Publication:
Marsden AE, et al., 2016. Inhibition of Pseudomonas aeruginosa ExsA DNA-Binding Activity by N-Hydroxybenzimidazoles. Antimicrob Agents Chemother 60(2):766-76.