Drug details:
Molecular formula: C₁₆H₁₈N₂O₃

Standard name: N-cyclohexyl-2-(2,3-dioxoindol-1-yl)acetamide

Synonyms:

N-cyclohexyl-2-(2,3-dioxoindol-1-yl)acetamide N-Cyclohexyl-2,3-dioxoindoline-1-acetamide N-cyclohexyl-2-(2,3-dioxoindolin-1-yl)acetamide

Curated SMILES: C1CCC(CC1)NC(=O)CN2C3=CC=CC=C3C(=O)C2=O

Evidence for compound's anti-virulence activity:

Pseudomonas
Related VFcategory: Biofilm
Target: Not determined
Drug effect: Inhibits a series of virulence factors such as quorum sensing, swarming and synthesis of pyocyanin, pyochelin and pyoverdine.
Max phase: Preclinical (in vitro)
Publication:
von Ambüren J, et al., 2020. Comprehensive Host Cell-Based Screening Assays for Identification of Anti-Virulence Drugs Targeting Pseudomonas aeruginosa and Salmonella Typhimurium. Microorganisms 8(8):1096.