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7-hydroxyindole

Drug details:
Molecular formula: C8H7NO

Standard name: 1H-indol-7-ol
Classification: Hydroxyindoles; Indoles and derivatives; Organoheterocyclic compounds; Organic compounds;
Synonyms:  1H-indol-7-ol
7-hydroxy indole
7-hydroxy-indole
7-hydroxyindole, AldrichCPR

Curated SMILES: C1=CC2=C(C(=C1)O)NC=C2
Chemical structure:
Depiction based on curated SMILES OH N H

Pseudomonas
Related VFcategory: Biofilm
Target: Not determined
Drug effect: Inhibits a series of virulence factors such as quorum sensing, swarming and synthesis of pyocyanin, pyochelin and pyoverdine.
Max phase: In vivo
Publication:
Lee J, et al., 2009. Indole and 7-hydroxyindole diminish Pseudomonas aeruginosa virulence. Microb Biotechnol 2(1):75-90.








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