Drug details:
Molecular formula: C₁₆H₁₁N₅O₂

Standard name: N-(4-cyanophenyl)-N'-(6-cyanopyridin-3-yl)propanediamide

Curated SMILES: N#CC1=CC=C(NC(=O)CC(=O)NC2=CC=C(C#N)N=C2)C=C1

Pseudomonas
Related VFcategory: Biofilm
Target: MvfR
Drug effect: Inhibits MvfR-regulated virulence functions.
Max phase: In vitro
Publication:
Singh VK, et al., 2022. Tackling recalcitrant Pseudomonas aeruginosa infections in critical illness via anti-virulence monotherapy. Nat Commun 13(1):5103.