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N-benzyl-2-{[5,6-bis(4-methylphenyl)-1,2,4-triazin-3-yl]thio}acetamide

Drug details:
Molecular formula: C26H24N4OS

Classification: Aryl thioethers; Thioethers; Organosulfur compounds; Organic compounds;
Chemical structure:
Depiction based on curated SMILES CH 3 N CH 3 NH O S N N

Pseudomonas
Related VFcategory: Biofilm
Target: MvfR
Drug effect: Inhibits MvfR-regulated virulence functions.
Max phase: In vitro
Publication:
Starkey M, et al., 2014. Identification of anti-virulence compounds that disrupt quorum-sensing regulated acute and persistent pathogenicity. PLoS Pathog 10(8):e1004321.








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