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5-nitro-7-[(3-phenylpyrrolidin-1-yl)methyl]quinolin-8-ol

Drug details:
Molecular formula: C20H19N3O3

Classification: Nitroquinolines and derivatives; Quinolines and derivatives; Organoheterocyclic compounds; Organic compounds;
Chemical structure:
Depiction based on curated SMILES N OH O N _ O + N

Chlamydia
Related VF: TTSS (Type III secretion system)
Target: Not determined
Drug effect: Inhibits T3SS activity.
Max phase: In vitro
Publication:
Enquist PA, et al., 2012. Derivatives of 8-hydroxyquinoline--antibacterial agents that target intra- and extracellular Gram-negative pathogens. Bioorg Med Chem Lett 22(10):3550-3.








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