Drug details:
Molecular formula: C₁₀H₉N₃OS₂

Standard name: 3-prop-2-enylsulfanyl-6-thiophen-2-yl-4H-1,2,4-triazin-5-one

Curated SMILES: C=CCSC1=NN=C(C2=CC=CS2)C(O)=N1

Klebsiella
Related VF: Capsule; LPS
Target: Not determined
Drug effect: Prevents biosynthesis of the Klebsiella capsule and lipopolysaccharides.
Max phase: In vivo
Publication:
Benghezal M, et al., 2007. Inhibitors of bacterial virulence identified in a surrogate host model. Cell Microbiol 9(5):1336-42.

Pseudomonas
Related VF: LPS
Target: Not determined
Drug effect: Prevents biosynthesis of the capsule and lipopolysaccharides.
Max phase: In vivo
Publication:
Benghezal M, et al., 2007. Inhibitors of bacterial virulence identified in a surrogate host model. Cell Microbiol 9(5):1336-42.