Drug details:
Molecular formula: C₂₄H₂₃N₇O₄

Standard name: 4-methyl-2-(4-methylphenyl)-6-[5-(4-phenylpiperazine-1-carbonyl)-1,2,4-oxadiazol-3-yl]-1,2,4-triazine-3,5-dione

Curated SMILES: CC1=CC=C(N2N=C(C3=NOC(C(=O)N4CCN(C5=CC=CC=C5)CC4)=N3)C(=O)N(C)C2=O)C=C1

Shigella
Related VF: TTSS (Type III secretion system)
Target: Spa47/IpaC
Drug effect: Inhibits transcriptional activator.
Max phase: In vivo
Publication:
Case HB, et al., 2020. Novel Noncompetitive Type Three Secretion System ATPase Inhibitors Shut Down Shigella Effector Secretion. Biochemistry 59(28):2667-2678.