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4-(4,5-Di([1,1'-biphenyl]-4-yl)-1H-imidazol-2-yl)benzoic acid

Drug details:
Molecular formula: C34H24N2O2

Classification: Biphenyls and derivatives; Benzene and substituted derivatives; Benzenoids; Organic compounds;
Synonyms:  4-(4,5-di(biphenyl-4-yl)-1H-imidazol-2-yl)benzoic acid
4-[4,5-di(biphenyl-4-yl)-1H-imidazol-2-yl]benzoic acid
4-(4,5-dibiphenyl-4-yl-1{H}-imidazol-2-yl)benzoic acid

Chemical structure:
Depiction based on curated SMILES N H OH N O

Yersinia
Related VF: TTSS secreted effectors
Target: YopH
Drug effect: Targets the phosphotyrosine-binding pocket of YopH.
Max phase: In vitro
Publication:
Hu X, et al., 2013. Inhibitors of the Yersinia protein tyrosine phosphatase through high throughput and virtual screening approaches. Bioorg Med Chem Lett 23(4):1056-62.








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