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(Z)-5-(5-((2,4-dioxothiazolidin-5-ylidene)methyl)furan-2-yl)-2-hydroxybenzoic acid

Drug details:
Molecular formula: C15H9NO6S

Classification: Benzoic acids and derivatives; Benzene and substituted derivatives; Benzenoids; Organic compounds;
Synonyms:  5-[5-[(Z)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]furan-2-yl]-2-hydroxybenzoic acid
5-(5-{[(5Z)-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}furan-2-yl)-2-hydroxybenzoic acid
5-[5-(2,4-Dioxothiazolidine-5-ylidenemethyl)-2-furanyl]-2-hydroxybenzoic acid

Chemical structure:
Depiction based on curated SMILES S O OH HO O O O HN

Yersinia
Related VF: TTSS secreted effectors
Target: YopH
Drug effect: Targets the phosphotyrosine-binding pocket of YopH.
Max phase: In vitro
Publication:
Tautz L, et al., 2005. Inhibition of Yersinia tyrosine phosphatase by furanyl salicylate compounds. J Biol Chem 280(10):9400-8.








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