Escherichia
Related VF: Type 1 fimbriae; P fimbriae
Target: PapD
Drug effect: Blocking chaperone and usher functions.
Max phase: In vivo
Publication: Pinkner JS, et al., 2006. Rationally designed small compounds inhibit pilus biogenesis in uropathogenic bacteria. Proc Natl Acad Sci U S A 103(47):17897-902.