Drug details:
Molecular formula: C₂₅H₃₂N₂O₈

Standard name: [3,4,5-trihydroxy-6-[2-methyl-4-[3-(methylcarbamoyl)phenyl]phenoxy]oxan-2-yl]methyl 2-(dimethylamino)acetate

Curated SMILES: CNC(=O)C1=CC(C2=CC=C(OC3OC(COC(=O)CN(C)C)C(O)C(O)C3O)C(C)=C2)=CC=C1

Escherichia
Related VF: Type 1 fimbriae
Target: FimH
Drug effect: Bound to the FimH lectin domain to interfere with bacterial adhesion, invasion and biofilm formation.
Max phase: In vivo
Publication:
Mydock-McGrane L, et al., 2016. Antivirulence C-Mannosides as Antibiotic-Sparing, Oral Therapeutics for Urinary Tract Infections. J Med Chem 59(20):9390-9408.