Drug details:
Molecular formula: C₂₂H₂₄O₁₀

Standard name: dimethyl 5-[4-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]benzene-1,3-dicarboxylate

Curated SMILES: COC(=O)C1=CC(=CC(=C1)C2=CC=C(C=C2)O[C@@H]3[C@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)C(=O)OC

Escherichia
Related VF: Type 1 fimbriae
Target: FimH
Drug effect: Bound to the FimH lectin domain to interfere with bacterial adhesion, invasion and biofilm formation.
Max phase: In vitro
Publication:
Han Z, et al., 2010. Structure-based drug design and optimization of mannoside bacterial FimH antagonists. J Med Chem 53(12):4779-92.