Drug details:
Molecular formula: C₂₂H₂₂N₂O₃S

Standard name: 8-(dimethylamino)-7-[(4-methylnaphthalen-1-yl)methyl]-5-oxo-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridine-3-carboxylic acid

Curated SMILES: CC1=CC=C(C2=CC=CC=C12)CC3=CC(=O)N4C(CSC4=C3N(C)C)C(=O)O

Listeria
Related VF: PrfA (Pleiotropic regulatory factor)
Target: PrfA
Drug effect: Binds to PrfA, the master virulence regulator to decrease virulence factor expression.
Max phase: In vitro
Publication:
Kulén M, et al., 2018. Structure-Based Design of Inhibitors Targeting PrfA, the Master Virulence Regulator of Listeria monocytogenes. J Med Chem 61(9):4165-4175.