Drug details:
Molecular formula: C₁₄H₁₂N₂O

Standard name: 2-methoxyacridin-9-amine

Synonyms:

ACRIDINE, 9-AMINO-2-METHOXY- 9-Acridinamine, 2-methoxy- 9-amino-2-methoxyacridine 2-Methoxy-9-acridinamine 5-Amino-3-methoxyacridine (European) 5-Amino-3-methoxyacridine WLN: T C666 BNJ EO1 IZ

Curated SMILES: COC1=CC2=C(C=C1)N=C1C=CC=CC1=C2N

Brucella
Related VF: VirB type IV secretion system
Target: VirB8
Drug effect: Inhibits T4SS by targeting an essential assembly protein VirB8.
Max phase: In vivo
Publication:
Paschos A, et al., 2011. An in vivo high-throughput screening approach targeting the type IV secretion system component VirB8 identified inhibitors of Brucella abortus 2308 proliferation. Infect Immun 79(3):1033-43.