Drug details:
Molecular formula: C₁₅H₁₁Cl₂N₃O₇P₂

Standard name: [6-[(3,4-dichlorophenyl)carbamoyl]-3-phosphonoquinoxalin-2-yl]phosphonic acid

Curated SMILES: O=C(NC1=CC(Cl)=C(Cl)C=C1)C1=CC=C2N=C(P(=O)(O)O)C(P(=O)(O)O)=NC2=C1

Bacillus
Related VF: Collagenase
Target: ColQ1;ColA
Drug effect: Binds to bacterial collagenase to inhibit their activity thus to maintain the cell attachment, cell morphology, and cell viability.
Max phase: In vitro
Publication:
Alhayek A, et al., 2022. Discovery and Characterization of Synthesized and FDA-Approved Inhibitors of Clostridial and Bacillary Collagenases. J Med Chem 65(19):12933-12955.

Clostridium
Related VF: Collagenase
Target: ColG;ColH
Drug effect: Binds to bacterial collagenase to inhibit their activity thus to maintain the cell attachment, cell morphology, and cell viability.
Max phase: In vitro
Publication:
Alhayek A, et al., 2022. Discovery and Characterization of Synthesized and FDA-Approved Inhibitors of Clostridial and Bacillary Collagenases. J Med Chem 65(19):12933-12955.