Drug details:
Molecular formula: C₂₃H₂₆N₆O₅

Standard name: N-[2-[4-[(2-acetamidophenoxy)methyl]triazol-1-yl]ethyl]-2-benzyl-N'-hydroxypropanediamide

Curated SMILES: CC(=O)NC1=CC=CC=C1OCC2=CN(N=N2)CCNC(=O)C(CC3=CC=CC=C3)C(=O)NO

Bacillus
Related VF: Collagenase
Target: ColQ1;ColA
Drug effect: Binds to bacterial collagenase to inhibit their activity thus to maintain the cell attachment, cell morphology, and cell viability.
Max phase: In vitro
Publication:
Alhayek A, et al., 2022. Discovery and Characterization of Synthesized and FDA-Approved Inhibitors of Clostridial and Bacillary Collagenases. J Med Chem 65(19):12933-12955.

Clostridium
Related VF: Collagenase
Target: ColG;ColH
Drug effect: Binds to bacterial collagenase to inhibit their activity thus to maintain the cell attachment, cell morphology, and cell viability.
Max phase: In vitro
Publication:
Alhayek A, et al., 2022. Discovery and Characterization of Synthesized and FDA-Approved Inhibitors of Clostridial and Bacillary Collagenases. J Med Chem 65(19):12933-12955.