Drug details:
Classification: Amino acids, peptides, and analogues; Carboxylic acids and derivatives; Organic acids and derivatives; Organic compounds;

Curated SMILES: O=C1C=CC(=O)C(C2NC(=O)C(CC3=CC=CC=C3)NC2=O)=C1

Burkholderia
Related VF: Quorum-sensing
Target: CepI
Drug effect: Inhibits acyl-HSL synthase CepI activity.
Max phase: In vivo
Publication:
Scoffone VC, et al., 2016. Discovery of new diketopiperazines inhibiting Burkholderia cenocepacia quorum sensing in vitro and in vivo. Sci Rep 6:32487.