Drug details:
Molecular formula: C₅H₄N₄S₂

Standard name: 7,9-dihydro-3H-purine-2,8-dithione

Synonyms:

Dithiopurine Purinedithiol NSC29193

Curated SMILES: C1=NC(=S)NC2=C1NC(=S)N2

Bordetella
Related VF: Ptx (Pertussis toxin)
Target: PtxS1
Drug effect: Inhibits the ADP-ribosyltransferase activity pertussis AB5 holotoxin by binding at the NAD+-binding pocket of PtxS1.
Max phase: In vitro
Publication:
Ashok Y, et al., 2020. Discovery of Compounds Inhibiting the ADP-Ribosyltransferase Activity of Pertussis Toxin. ACS Infect Dis 6(4):588-602.