Drug details:
Molecular formula: C₂₁H₁₉BrN₂O₄

Standard name: ethyl 2-[(4Z)-4-[(3-bromo-4-methoxyphenyl)methylidene]-5-oxo-1-phenylpyrazol-3-yl]acetate

Curated SMILES: CCOC(=O)CC\1=NN(C(=O)/C1=C\C2=CC(=C(C=C2)OC)Br)C3=CC=CC=C3

Haemophilus
Related VF: LOS
Target: LgtC
Drug effect: Inhibits α-1,4-galactosyltransferase LgtC.
Max phase: In vitro
Publication:
Xu Y, et al., 2018. Structure-activity relationships in a new class of non-substrate-like covalent inhibitors of the bacterial glycosyltransferase LgtC. Bioorg Med Chem 26(11):2973-2983.