Drug details:
Classification: Benzoylindoles; Indoles and derivatives; Organoheterocyclic compounds; Organic compounds;

Curated SMILES: CN(C)C1=CC=C(C(=O)N2C3=CC=C(S(=O)(=O)O)C=C3C3=C2CCSC3)C=C1

Mycobacterium
Related VFcategory: Exoenzyme
Target: PtpB
Drug effect: Inhibits protein tyrosine phosphatase B (PtpB) to interfere with signal transduction pathways in macrophages.
Max phase: In vitro
Publication:
Nören-Müller A, et al., 2006. Discovery of protein phosphatase inhibitor classes by biology-oriented synthesis. Proc Natl Acad Sci U S A 103(28):10606-11.