Drug details:
Molecular formula: C₂₆H₃₁N₃O

Standard name: (2Z)-5-[5-[(2Z)-hexa-2,5-dien-2-yl]-1H-pyrrol-2-yl]-2-[(5-hex-5-enyl-1H-pyrrol-2-yl)methylidene]-3-methoxypyrrole

Curated SMILES: C/C(=C/CC=C)/C1=CC=C(N1)C2=N/C(=C\C3=CC=C(N3)CCCCC=C)/C(=C2)OC

Mycobacterium
Related VFcategory: Exoenzyme
Target: PtpA
Drug effect: Inhibits protein tyrosine phosphatase PtpA to disrupt phagosome acidification and maturation.
Max phase: In vitro
Publication:
Manger M, et al., 2005. Discovery of Mycobacterium tuberculosis protein tyrosine phosphatase A (MptpA) inhibitors based on natural products and a fragment-based approach. Chembiochem 6(10):1749-53.