Drug details:
Molecular formula: C₁₃H₁₂ClNO₂

Standard name: 2-chloro-4-(2,5-dimethylpyrrol-1-yl)benzoic acid

Synonyms:

2-chloro-4-(2,5-dimethyl-1H-pyrrol-1-yl)benzoic acid 2-chloro-4-(2,5-dimethylpyrrol-1-yl)benzoic acid Benzoic acid, 2-chloro-4-(2,5-dimethyl-1H-pyrrol-1-yl)- 2-chloro-4-(2,5-dimethyl-1-pyrrolyl)benzoic acid 2-chloranyl-4-(2,5-dimethylpyrrol-1-yl)benzoic acid 2-chloro-4-(2,5-dimethyl-1h-pyrrol-1-yl)-benzoic acid 2-chloro-4-(2,5-dimethyl-1H-pyrrol-1-yl)benzoicacid

Curated SMILES: CC1=CC=C(N1C2=CC(=C(C=C2)C(=O)O)Cl)C

Mycobacterium
Related VFcategory: Exoenzyme
Target: PtpA
Drug effect: Inhibits protein tyrosine phosphatase PtpA to disrupt phagosome acidification and maturation.
Max phase: In vitro
Publication:
Manger M, et al., 2005. Discovery of Mycobacterium tuberculosis protein tyrosine phosphatase A (MptpA) inhibitors based on natural products and a fragment-based approach. Chembiochem 6(10):1749-53.