Drug details:
Molecular formula: C₁₄H₁₃NO₄

Standard name: 5-(2,5-dimethylpyrrol-1-yl)benzene-1,3-dicarboxylic acid

Synonyms:

5-(2,5-dimethylpyrrol-1-yl)benzene-1,3-dicarboxylic acid 5-(2,5-Dimethyl-1h-pyrrol-1-yl)isophthalic acid 5-(2,5-dimethylpyrrol-1-yl)isophthalic acid 5-(2,5-dimethyl-1-pyrrolyl)benzene-1,3-dicarboxylic acid 1,3-Benzenedicarboxylic acid, 5-(2,5-dimethyl-1H-pyrrol-1-yl)-

Curated SMILES: CC1=CC=C(N1C2=CC(=CC(=C2)C(=O)O)C(=O)O)C

Mycobacterium
Related VFcategory: Exoenzyme
Target: PtpA
Drug effect: Inhibits protein tyrosine phosphatase PtpA to disrupt phagosome acidification and maturation.
Max phase: In vitro
Publication:
Manger M, et al., 2005. Discovery of Mycobacterium tuberculosis protein tyrosine phosphatase A (MptpA) inhibitors based on natural products and a fragment-based approach. Chembiochem 6(10):1749-53.