Drug details:
Molecular formula: C₁₇H₁₂BrClN₄O

Standard name: N-[3-(2-aminopyrimidin-4-yl)phenyl]-3-bromo-5-chlorobenzamide

Curated SMILES: NC1=NC=CC(C2=CC=CC(NC(=O)C3=CC(Br)=CC(Cl)=C3)=C2)=N1

Evidence for compound's anti-virulence activity:

Staphylococcus
Related VFcategory: Biofilm
Target: Not determined
Drug effect: Inhibits biofilm formation (membrane disruption might be a possible mechanism).
Max phase: Preclinical (in vitro)
Publication:
Weig AW, et al., 2021. A scaffold hopping strategy to generate new aryl-2-amino pyrimidine MRSA biofilm inhibitors. RSC Med Chem 12(2):293-296.