Drug details:
Molecular formula: C₁₈H₁₈N₂O₄

Standard name: (E)-N-(3-formyl-4-morpholin-4-ylphenyl)-3-(furan-2-yl)prop-2-enamide

Curated SMILES: C1COCCN1C2=C(C=C(C=C2)NC(=O)/C=C/C3=CC=CO3)C=O

Staphylococcus
Related VFcategory: Others
Target: SrtA
Drug effect: Blocks sortase-catalyzed cleavage and transpeptidation reactions with LPXTG substrate peptides and inhibited the incorporation of surface proteins into the staphylococcal envelope.
Max phase: In vitro
Publication:
Chenna BC, et al., 2010. Synthesis and structure activity relationship studies of novel Staphylococcus aureus Sortase A inhibitors. Eur J Med Chem 45(9):3752-61.