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Mupirocin

Drug details:
Molecular formula: C26H44O9

Classification: Fatty acids and conjugates; Fatty Acyls; Lipids and lipid-like molecules; Organic compounds;
Synonyms:  Pseudomonic acid
Bactroban
Mupirocine
Centany
Pseudomonic acid A
Bactoderm
Mupirocina
Mupirocinum
Turixin
......

Chemical structure:
Depiction based on curated SMILES O O O HO H 3 C H H 3 C OH H H H O H H 3 C O H H H HO OH

Staphylococcus
Related VF: α-hemolysin
Target: Not determined
Drug effect: Inhibits α-toxin experession by down-regulating agr, saeRS and sarA.
Max phase: In vitro
Publication:
Jin Y, et al., 2018. Sub-Inhibitory Concentrations of Mupirocin Strongly Inhibit Alpha-Toxin Production in High-Level Mupirocin-Resistant MRSA by Down-Regulating agr, saeRS, and sarA. Front Microbiol 9:993.








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