Drug details:
Molecular formula: C₂₄H₁₅N₃O₂S₂

Standard name: 4-[4-[4-(4-nitrophenyl)-1,3-thiazol-2-yl]phenyl]-2-phenyl-1,3-thiazole

Curated SMILES: C1=CC=C(C=C1)C2=NC(=CS2)C3=CC=C(C=C3)C4=NC(=CS4)C5=CC=C(C=C5)[N+](=O)[O-]

Enterococcus
Related VFcategory: Others; Adherence; Biofilm
Target: SrtA
Drug effect: Inhibits SrtA-mediated adesion and biofilm formation.
Max phase: In vitro
Publication:
Oniga SD, et al., 2017. New 2-Phenylthiazoles as Potential Sortase A Inhibitors: Synthesis, Biological Evaluation and Molecular Docking. Molecules 22(11):1827.

Staphylococcus
Related VFcategory: Others; Adherence; Biofilm
Target: SrtA
Drug effect: Inhibits SrtA-mediated adesion and biofilm formation.
Max phase: In vitro
Publication:
Oniga SD, et al., 2017. New 2-Phenylthiazoles as Potential Sortase A Inhibitors: Synthesis, Biological Evaluation and Molecular Docking. Molecules 22(11):1827.