Drug details:
Molecular formula: C₂₅H₁₈N₂OS₂

Standard name: 4-(4-methoxyphenyl)-2-[4-(2-phenyl-1,3-thiazol-4-yl)phenyl]-1,3-thiazole

Curated SMILES: COC1=CC=C(C=C1)C2=CSC(=N2)C3=CC=C(C=C3)C4=CSC(=N4)C5=CC=CC=C5

Enterococcus
Related VFcategory: Others; Adherence; Biofilm
Target: SrtA
Drug effect: Inhibits SrtA-mediated adesion and biofilm formation.
Max phase: In vitro
Publication:
Oniga SD, et al., 2017. New 2-Phenylthiazoles as Potential Sortase A Inhibitors: Synthesis, Biological Evaluation and Molecular Docking. Molecules 22(11):1827.

Staphylococcus
Related VFcategory: Others; Adherence; Biofilm
Target: SrtA
Drug effect: Inhibits SrtA-mediated adesion and biofilm formation.
Max phase: In vitro
Publication:
Oniga SD, et al., 2017. New 2-Phenylthiazoles as Potential Sortase A Inhibitors: Synthesis, Biological Evaluation and Molecular Docking. Molecules 22(11):1827.