|
(2R)-2-[[3-(1-benzofuran-2-yl)phenyl]sulfonylamino]-N-hydroxy-4-methylpentanamide |
|
Clostridium |
BoNT (Botulinum neurotoxin) |
Preclinical (in vitro) |
Thompson JC, et al. 2020. Bioorg Med Chem |
|
(2R,3R)-2-[[3-(1-benzofuran-2-yl)phenyl]sulfonylamino]-N-hydroxy-3-methylpentanamide |
Depiction based on curated SMILES
HO
N
H
O
O
CH
3
O
O
S
HN
H
H
3
C
H
|
Clostridium |
BoNT (Botulinum neurotoxin) |
Preclinical (in vitro) |
Thompson JC, et al. 2020. Bioorg Med Chem |
|
(2S)-2-[[3-(1-benzofuran-2-yl)phenyl]sulfonylamino]-N-hydroxyhexanamide |
Depiction based on curated SMILES
HO
N
H
O
O
CH
3
O
O
S
HN
H
|
Clostridium |
BoNT (Botulinum neurotoxin) |
Preclinical (in vitro) |
Thompson JC, et al. 2020. Bioorg Med Chem |
|
(2S,3S)-2-[[3-(1-benzofuran-2-yl)phenyl]sulfonylamino]-N-hydroxy-3-methylpentanamide |
Depiction based on curated SMILES
OH
N
H
O
O
H
3
C
O
O
S
N
H
H
3
C
|
Clostridium |
BoNT (Botulinum neurotoxin) |
Preclinical (in vitro) |
Thompson JC, et al. 2020. Bioorg Med Chem |
|
3-(1-benzofuran-2-yl)-N-[(2R)-1-(hydroxyamino)-4-methyl-1-oxopentan-2-yl]benzamide |
Depiction based on curated SMILES
HO
NH
O
O
H
3
C
O
N
H
H
CH
3
|
Clostridium |
BoNT (Botulinum neurotoxin) |
Preclinical (in vitro) |
Thompson JC, et al. 2020. Bioorg Med Chem |
|
3-(1-benzofuran-2-yl)-N-[(2R,3R)-1-(hydroxyamino)-3-methyl-1-oxopentan-2-yl]benzamide |
Depiction based on curated SMILES
HO
NH
O
O
H
3
C
O
N
H
H
H
3
C
H
|
Clostridium |
BoNT (Botulinum neurotoxin) |
Preclinical (in vitro) |
Thompson JC, et al. 2020. Bioorg Med Chem |
|
3-(1-benzofuran-2-yl)-N-[(2S,3S)-1-(hydroxyamino)-3-methyl-1-oxopentan-2-yl]benzamide |
Depiction based on curated SMILES
HO
N
H
O
O
CH
3
O
N
H
CH
3
|
Clostridium |
BoNT (Botulinum neurotoxin) |
Preclinical (in vitro) |
Thompson JC, et al. 2020. Bioorg Med Chem |
|
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