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General information:
 Ubiquitous bacteria that belong to the γ-Proteobacteria.
Contains the clinically important human pathogen P. aeruginosa, the agriculturally important plant pathogen P. syringae, and the nonpathogenic bioremediation agent P. putida.
Characteristics:
P. aeruginosa is a major opportunistic human pathogen, notable for its ability to form biofilm and best-characterized quorum-sensing systems among Gram-negative bacteria.
Disease:
P. aeruginosa can cause a variety of opportunistic infections ranging from eye infections in contact lens wearers to burn and wound infections leading to septic shock.
Lung infections in cystic fibrosis patients.
Selected genomes: ⇒ comparative pathogenomics ⇐
P. aeruginosa LESB58, 6601757 bp, NC_011770
P. aeruginosa PA7, 6588339 bp, NC_009656
P. aeruginosa PAO1, 6264404 bp, NC_002516
P. aeruginosa UCBPP-PA14, 6537648 bp, NC_008463
P. entomophila L48, 5888780 bp, NC_008027
P. fluorescens Pf-5, 7074893 bp, NC_004129
P. fluorescens Pf0-1, 6438405 bp, NC_007492
P. fluorescens SBW25, 6722539 bp, NC_012660
P. mendocina ymp, 5072807 bp, NC_009439
P. putida F1, 5959964 bp, NC_009512
P. putida GB-1, 6078430 bp, NC_010322
P. putida KT2440, 6181863 bp, NC_002947
P. putida W619, 5774330 bp, NC_010501
P. stutzeri A1501, 4567418 bp, NC_009434
P. syringae pv. phaseolicola 1448A, 5928787 bp, NC_005773
P. syringae pv. syringae B728a, 6093698 bp, NC_007005
P. syringae pv. tomato str. DC3000, 6397126 bp, NC_004578
Plasmids:
P. syringae pv. phaseolicola 1448A large plasmid, 131950 bp, NC_007274
P. syringae pv. tomato str. DC3000 pDC3000A, 73661 bp, NC_004633
Related publications:
 Stover CK, et al., 2000. Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen. Nature 406(6799):959-964.
Nelson KE, et al., 2002. Complete genome sequence and comparative analysis of the metabolically versatile Pseudomonas putida KT2440. Environ. Microbiol. 4(12):799-808.
Buell CR, et al., 2003. The complete genome sequence of the Arabidopsis and tomato pathogen Pseudomonas syringae pv. tomato DC3000. Proc. Natl. Acad. Sci. USA. 100(18):10181-10186.
Paulsen IT, et al., 2005. Complete genome sequence of the plant commensal Pseudomonas fluorescens Pf-5. Nat Biotechnol. 23(7):873-878.
Feil H, et al., 2005. Comparison of the complete genome sequences of Pseudomonas syringae pv. syringae B728a and pv. tomato DC3000. Proc. Natl. Acad. Sci. USA. 102(31):11064-11069.
Joardar V, et al., 2005. Whole-genome sequence analysis of Pseudomonas syringae pv. phaseolicola 1448A reveals divergence among pathovars in genes involved in virulence and transposition. J. Bacteriol. 187(18):6488-6498.
Vodovar N, et al., 2006. Complete genome sequence of the entomopathogenic and metabolically versatile soil bacterium Pseudomonas entomophila. Nat Biotechnol 24(6):673-679.
Lee DG, et al., 2006. Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial. Genome Biol 7(10):R90.
Yan Y, et al., 2008. Nitrogen fixation island and rhizosphere competence traits in the genome of root-associated Pseudomonas stutzeri A1501. Proc Natl Acad Sci USA 105(21):7564-7569.
Winstanley C, et al., 2009. Newly introduced genomic prophage islands are critical determinants of in vivo competitiveness in the Liverpool Epidemic Strain of Pseudomonas aeruginosa. Genome Res 19(1):12-23.
Silby MW, et al., 2009. Genomic and genetic analyses of diversity and plant interactions of Pseudomonas fluorescens. Genome Biol 10(5):R51.
Roy PH, et al., 2010. Complete genome sequence of the multiresistant taxonomic outlier Pseudomonas aeruginosa PA7. PLoS One 5(1):e8842.
Major virulence factors in Pseudomonas:
Genomic location of virulence-related genes in Pseudomonas:
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Reported anti-virulence compounds to Pseudomonas:
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