Home
 Search
 Category
 Compounds
 Status
 Download
 Contacts
 Resources


Compound category: Benzimidazoles
(total 26 related compounds in database, current show from 1 to 10)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
(2Z)-2-(3-chloro-5-ethoxy-4-hydroxybenzylidene)-7,8-dimethyl[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-one Depiction based on curated SMILES H 3 C OH Cl O N H 3 C CH 3 N S O Pseudomonas
Yersinia		 TTSS (Type III secretion system)
TTSS (Type III secretion system)		 Preclinical (in vitro)
Preclinical (in vitro)		 Harmon DE, et al. 2010. Antimicrob Agents Chemother
(5R,6R)-5,6-bis[[4-(phenoxymethyl)triazol-1-yl]methyl]-4,5,6,7-tetrahydro-1H-benzimidazol-2-amine Depiction based on curated SMILES O N N H N N N N HN N H NH 2 O Acinetobacter
Pseudomonas		 Biofilm
Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)		 Huigens RW 3rd, et al. 2009. Org Biomol Chem
(E)-3-(4-Acetyl-phenyl)-N-[4-(1-hydroxy-6-nitro-1H-benzoimidazol-2-yl)-phenyl]-acrylamide Depiction based on curated SMILES N + N O _ O N HO H 3 C N H O O Pseudomonas TTSS (Type III secretion system) Preclinical (in vitro) Marsden AE, et al. 2016. Antimicrob Agents Chemother
(E)-3-(4-acetylphenyl)-N-(4-(6-cyano-1-hydroxy-1H-benzo[d]imidazol-2-yl)phenyl)acrylamide Depiction based on curated SMILES HO N N N H 3 C N H O O Pseudomonas TTSS (Type III secretion system) Preclinical (in vitro) Marsden AE, et al. 2016. Antimicrob Agents Chemother
(E)-3-(4-fluorophenyl)-N-[4-(1-hydroxy-6-nitrobenzimidazol-2-yl)phenyl]prop-2-enamide Depiction based on curated SMILES HO N _ O O + N N O N H F Pseudomonas
Yersinia
Yersinia		 TTSS (Type III secretion system)
TTSS (Type III secretion system)
TTSS (Type III secretion system)		 Preclinical (in vitro)
Preclinical (in vitro)
Preclinical (in vivo)		 Marsden AE, et al. 2016. Antimicrob Agents Chemother
Kim OK, et al. 2009. J Med Chem
Garrity-Ryan LK, et al. 2010. Infect Immun
2,2,2-trifluoro-N-[2-[2-(4-iodoanilino)-2-oxoethyl]sulfanyl-3H-benzimidazol-5-yl]acetamide Depiction based on curated SMILES F I NH N H F O F O HN N S Pseudomonas Biofilm Preclinical (in vitro) Starkey M, et al. 2014. PLoS Pathog
2-(1H-benzimidazol-2-ylsulfanyl)-N-(3,4-dichlorophenyl)acetamide Depiction based on curated SMILES Cl Cl NH N H O N S Pseudomonas Biofilm Preclinical (in vitro) Starkey M, et al. 2014. PLoS Pathog
2-(1H-benzimidazol-2-ylthio)-N-[3-(methylthio)phenyl]acetamide Depiction based on curated SMILES S N H N CH 3 O N H S Pseudomonas Biofilm Preclinical (in vitro) Starkey M, et al. 2014. PLoS Pathog
2-(1H-benzimidazol-2-ylsulfanyl)-N-(4-bromophenyl)acetamide Depiction based on curated SMILES Br HN N H O N S Pseudomonas Biofilm Preclinical (in vitro) Starkey M, et al. 2014. PLoS Pathog
Acetamide, 2-(1H-benzimidazol-2-ylthio)-N-(4-chlorophenyl)- Depiction based on curated SMILES Cl HN N H O N S Pseudomonas Biofilm Preclinical (in vitro) Starkey M, et al. 2014. PLoS Pathog
   


NOTE: for more interactive and statistic charts, please visit the JavaScript-rich interface of VFDB.



Page  1  2  3 



Back to top
2004-2024 NIPB, CAMS&PUMC