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2-(1H-benzimidazol-2-ylthio)-N-[3-(methylthio)phenyl]acetamide

Drug details:
Molecular formula: C16H15N3OS2

Classification: Benzimidazoles; Organoheterocyclic compounds; Organic compounds;
Synonyms:  2-(1H-Benzimidazol-2-ylsulfanyl)-N-[3-(methylsulfanyl)phenyl]acetamide
2-(1H-Benzimidazol-2-ylsulfanyl)-N-[3-(methylsulfanyl)phenyl]acetamide #
Acetamide, 2-(1H-benzoimidazol-2-ylsulfanyl)-N-(3-methylsulfanylphenyl)-

Chemical structure:
Depiction based on curated SMILES S N H N CH 3 O N H S

Evidence for compound's anti-virulence activity:

Pseudomonas
Related VFcategory: Biofilm
Target: MvfR
Drug effect: Inhibits MvfR-regulated virulence functions.
Max phase: Preclinical (in vitro)
Publication:
Starkey M, et al., 2014. Identification of anti-virulence compounds that disrupt quorum-sensing regulated acute and persistent pathogenicity. PLoS Pathog 10(8):e1004321.








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