Drug details:
Molecular formula: C₂₀H₁₇ClN₂O₃S

Standard name: (2Z)-2-[(3-chloro-5-ethoxy-4-hydroxyphenyl)methylidene]-5,6-dimethyl-[1,3]thiazolo[3,2-a]benzimidazol-1-one

Synonyms:

2-(3-chloro-5-ethoxy-4-hydroxybenzylidene)-7,8-dimethyl[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-one 2-[(Z)-1-(3-chloro-5-ethoxy-4-hydroxyphenyl)methylidene]-7,8-dimethyl[1,3]thiazolo[3,2-a][1,3]benzimidazol-3-one

Curated SMILES: CCOC1=CC(/C=C2\SC3=NC4=C(C)C(C)=CC=C4N3C2=O)=CC(Cl)=C1O

Evidence for compound's anti-virulence activity:

Pseudomonas
Related VF: TTSS (Type III secretion system)
Target: Not determined
Drug effect: Blocks translocation of effectors into host cells.
Max phase: Preclinical (in vitro)
Publication:
Harmon DE, et al., 2010. Identification and characterization of small-molecule inhibitors of Yop translocation in Yersinia pseudotuberculosis. Antimicrob Agents Chemother 54(8):3241-54.

Yersinia
Related VF: TTSS (Type III secretion system)
Target: Yops
Drug effect: Inhibits translocation of Yop effectors.
Max phase: Preclinical (in vitro)
Publication:
Harmon DE, et al., 2010. Identification and characterization of small-molecule inhibitors of Yop translocation in Yersinia pseudotuberculosis. Antimicrob Agents Chemother 54(8):3241-54.