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2,2,2-trifluoro-N-[2-[2-(4-iodoanilino)-2-oxoethyl]sulfanyl-3H-benzimidazol-5-yl]acetamide

Drug details:
Molecular formula: C17H12F3IN4O2S

Classification: Benzimidazoles; Organoheterocyclic compounds; Organic compounds;
Chemical structure:
Depiction based on curated SMILES F I NH N H F O F O HN N S

Evidence for compound's anti-virulence activity:

Pseudomonas
Related VFcategory: Biofilm
Target: MvfR
Drug effect: Inhibits MvfR-regulated virulence functions.
Max phase: Preclinical (in vitro)
Publication:
Starkey M, et al., 2014. Identification of anti-virulence compounds that disrupt quorum-sensing regulated acute and persistent pathogenicity. PLoS Pathog 10(8):e1004321.








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