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Acetamide, 2-(1H-benzimidazol-2-ylthio)-N-(4-chlorophenyl)-

Drug details:
Molecular formula: C15H12ClN3OS

Classification: Benzimidazoles; Organoheterocyclic compounds; Organic compounds;
Synonyms:  2-((1H-benzo[d]imidazol-2-yl)thio)-N-(4-chlorophenyl)acetamide
2-(1H-benzimidazol-2-ylsulfanyl)-N-(4-chlorophenyl)acetamide
2-(1H-1,3-BENZODIAZOL-2-YLSULFANYL)-N-(4-CHLOROPHENYL)ACETAMIDE
2-(1H-Benzimidazol-2-ylthio)-N-(4-chlorophenyl)acetamide
2-(1H-Benzoimidazol-2-ylsulfanyl)-N-(4-chloro-phenyl)-acetamide

Chemical structure:
Depiction based on curated SMILES Cl HN N H O N S

Evidence for compound's anti-virulence activity:

Pseudomonas
Related VFcategory: Biofilm
Target: MvfR
Drug effect: Inhibits MvfR-regulated virulence functions.
Max phase: Preclinical (in vitro)
Publication:
Starkey M, et al., 2014. Identification of anti-virulence compounds that disrupt quorum-sensing regulated acute and persistent pathogenicity. PLoS Pathog 10(8):e1004321.








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