Home
Search
Category
Compounds
Status
Download
Contacts
Resources



Compound category: Benzene and substituted derivatives
(total 19 related compounds in database, current show from 1 to 10)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
2-[(5-nitro-1H-benzimidazol-2-yl)sulfanyl]-N-(4-phenoxyphenyl)acetamide Depiction based on curated SMILES NH O NH O _ O O + N N S Pseudomonas Biofilm Preclinical (in vivo) Starkey M, et al. 2014. PLoS Pathog
Fluorothiazinon Depiction based on curated SMILES OH O S F F H 3 C NH O N N O Acinetobacter
Chlamydia
Klebsiella
Pseudomonas
Salmonella
Biofilm
TTSS (Type III secretion system)
Biofilm
TTSS (Type III secretion system)
TTSS (SPI-1 encode); TTSS (SPI-2 encode)
Preclinical (in vivo)
Preclinical (in vivo)
Preclinical (in vitro)
Preclinical (in vivo)
Phase II trial
Bondareva NE, et al. 2022. J Antibiot (Tokyo)
Zigangirova NA, et al. 2012. Acta Naturae; Koroleva EA, et al. 2015. Biomed Res Int; Zigangirova NA, et al. 2016. J Med Microbiol
Tsarenko SV, et al. 2023. J Antibiot (Tokyo)
Sheremet AB, et al. 2018. Biomed Res Int
Nesterenko LN, et al. 2016. J Antibiot (Tokyo); Zigangirova NA, et al. 2021. J Antibiot (Tokyo)
N-(4-cyanophenyl)-2-fluoro-N'-(4-phenoxyphenyl)propanediamide Depiction based on curated SMILES O N N H O F O HN Pseudomonas Biofilm Preclinical (in vivo) Singh VK, et al. 2022. Nat Commun
ML364 Depiction based on curated SMILES S F F F S O O HN H 3 C O N H N Klebsiella
Pseudomonas
Staphylococcus
Biofilm; Biofilm
Pyocyanin
Biofilm
Preclinical (in vivo)
Preclinical (in vivo)
Preclinical (in vivo)
Zhang Y, et al. 2022. Front Microbiol

2-fluoro-N-(4-phenoxyphenyl)-N'-[4-(trifluoromethyl)phenyl]propanediamide Depiction based on curated SMILES O F F F F NH O N H O Pseudomonas Biofilm Preclinical (in vitro) Singh VK, et al. 2022. Nat Commun
3-(2-amino-1H-imidazol-5-yl)-N-(4-phenylbutyl)propanamide;hydrochloride Depiction based on curated SMILES ClH NH 2 HN N O NH Pseudomonas Biofilm Preclinical (in vitro) Ballard TE, et al. 2008. Chemistry
3-(2-amino-1H-imidazol-5-yl)-N-[2-(4-bromophenyl)ethyl]propanamide;hydrochloride Depiction based on curated SMILES O ClH Br NH 2 HN N NH Pseudomonas Biofilm Preclinical (in vitro) Ballard TE, et al. 2008. Chemistry
N'-(3-chloro-4-cyanophenyl)-N-(4-cyanophenyl)propanediamide Depiction based on curated SMILES N H Cl N N O O HN Pseudomonas Biofilm Preclinical (in vitro) Singh VK, et al. 2022. Nat Commun
N'-(4-bromophenyl)-N-(4-cyanophenyl)propanediamide Depiction based on curated SMILES O Br N H N O NH Pseudomonas Biofilm Preclinical (in vitro) Singh VK, et al. 2022. Nat Commun
N'-(4-chlorophenyl)-N-(4-cyanophenyl)propanediamide Depiction based on curated SMILES O Cl N H N O NH Pseudomonas Biofilm Preclinical (in vitro) Singh VK, et al. 2022. Nat Commun
   


NOTE: for more interactive and statistic charts, please visit the JavaScript-rich interface of VFDB.



Page  1  2 



Back to top
2004-2024 NIPB, CAMS&PUMC