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Compound category: Benzene and substituted derivatives
(total 19 related compounds in database, current show from 11 to 19)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
N,N'-bis(4-cyanophenyl)-2-methylpropanediamide Depiction based on curated SMILES N N H O CH 3 N NH O Pseudomonas Biofilm Preclinical (in vitro) Singh VK, et al. 2022. Nat Commun
N,N'-bis(4-cyanophenyl)propanediamide Depiction based on curated SMILES O N NH N O N H Pseudomonas Biofilm Preclinical (in vitro) Singh VK, et al. 2022. Nat Commun
N-(2,4-dimethoxyphenyl)-2-[(5-nitro-1H-benzimidazol-2-yl)thio]acetamide Depiction based on curated SMILES CH 3 O N H _ O O + N H 3 C N S O HN O Pseudomonas Biofilm Preclinical (in vitro) Starkey M, et al. 2014. PLoS Pathog
N-(4-cyanophenyl)-N'-(4-phenoxyphenyl)propanediamide Depiction based on curated SMILES O N N H O O NH Pseudomonas Biofilm Preclinical (in vitro) Singh VK, et al. 2022. Nat Commun
N-(4-cyanophenyl)-N'-(6-cyanopyridin-3-yl)propanediamide Depiction based on curated SMILES O N N NH N O N H Pseudomonas Biofilm Preclinical (in vitro) Singh VK, et al. 2022. Nat Commun
N-(4-cyanophenyl)-N'-[4-(trifluoromethyl)phenyl]propanediamide Depiction based on curated SMILES NH F F F N O O N H Pseudomonas Biofilm Preclinical (in vitro) Singh VK, et al. 2022. Nat Commun
N-phenyl-2-{[4-(thiophen-2-yl)pyrimidin-2-yl]sulfanyl}acetamide Depiction based on curated SMILES NH N S O N S Pseudomonas Biofilm Preclinical (in vitro) Starkey M, et al. 2014. PLoS Pathog
N-[4-(2-amino-1H-imidazol-5-yl)phenyl]-3,5-difluorobenzamide;hydrochloride Depiction based on curated SMILES N H ClH F F O H 2 N N H N Escherichia
Pseudomonas		 Biofilm
Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)		 Bunders CA, et al. 2010. Bioorg Med Chem Lett
5beta,6alpha-Bis[4-(benzoylaminomethyl)-1H-1,2,3-triazole-1-ylmethyl]-4,5,6,7-tetrahydro-1H-benzoimidazole-2-amine Depiction based on curated SMILES O N H N HN N N N N H N H N H 2 N N H O Pseudomonas Biofilm Preclinical (in vitro) Huigens RW 3rd, et al. 2009. Org Biomol Chem
   
   
   


NOTE: for more interactive and statistic charts, please visit the JavaScript-rich interface of VFDB.



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