Drug details:
Molecular formula: C₁₈H₁₄N₄O₂

Standard name: N,N'-bis(4-cyanophenyl)-2-methylpropanediamide

Curated SMILES: CC(C(=O)NC1=CC=C(C#N)C=C1)C(=O)NC1=CC=C(C#N)C=C1

Evidence for compound's anti-virulence activity:

Pseudomonas
Related VFcategory: Biofilm
Target: MvfR
Drug effect: Inhibits MvfR-regulated virulence functions.
Max phase: Preclinical (in vitro)
Publication:
Singh VK, et al., 2022. Tackling recalcitrant Pseudomonas aeruginosa infections in critical illness via anti-virulence monotherapy. Nat Commun 13(1):5103.