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Compound category: Anilides
(total 43 related compounds in database, current show from 1 to 10)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
Fluorothiazinon Depiction based on curated SMILES OH O S F F H 3 C NH O N N O Acinetobacter
Chlamydia
Klebsiella
Pseudomonas
Salmonella		 Biofilm
TTSS (Type III secretion system)
Biofilm
TTSS (Type III secretion system)
TTSS (SPI-1 encode); TTSS (SPI-2 encode)		 Preclinical (in vivo)
Preclinical (in vivo)
Preclinical (in vitro)
Preclinical (in vivo)
Phase II trial		 Bondareva NE, et al. 2022. J Antibiot (Tokyo)
Zigangirova NA, et al. 2012. Acta Naturae; Koroleva EA, et al. 2015. Biomed Res Int; Zigangirova NA, et al. 2016. J Med Microbiol
Tsarenko SV, et al. 2023. J Antibiot (Tokyo)
Sheremet AB, et al. 2018. Biomed Res Int
Nesterenko LN, et al. 2016. J Antibiot (Tokyo); Zigangirova NA, et al. 2021. J Antibiot (Tokyo)
1-phenyl-3-[4-(phenylsulfamoyl)phenyl]thiourea Depiction based on curated SMILES NH S N H O HN O S Escherichia
Salmonella		 Regulation
QseBC		 Preclinical (in vivo)
Preclinical (in vivo)		 Rasko DA, et al. 2008. Science
N-(2-carbamoylphenyl)quinoline-3-carboxamide Depiction based on curated SMILES O H 2 N O N H N Streptococcus Streptococcal glucosyltransferases Preclinical (in vivo) Nijampatnam B, et al. 2021. ACS Med Chem Lett
Compound 2
(internal name in literature)		 Depiction based on curated SMILES Cl Cl Cl H 2 N N O S O Bacillus Collagenase Preclinical (in vivo) Alhayek A, et al. 2022. Adv Ther (Weinh)
3-[(4-Methoxyanilino)carbonyl]-1,2,2-trimethylcyclopentanecarboxylic acid Depiction based on curated SMILES CH 3 CH 3 HO O CH 3 CH 3 O N H O Brucella VirB type IV secretion system Preclinical (in vivo) Paschos A, et al. 2011. Infect Immun
4-hydroxy-2-oxo-N,4-diphenylbut-3-enamide Depiction based on curated SMILES O N H O OH Brucella VirB type IV secretion system Preclinical (in vivo) Paschos A, et al. 2011. Infect Immun
N-[2-[4-[(2-acetamidophenoxy)methyl]triazol-1-yl]ethyl]-2-benzyl-N'-hydroxypropanediamide Depiction based on curated SMILES N H O O HN OH O NH H 3 C O N N N Bacillus
Clostridium		 Collagenase
Collagenase		 Preclinical (in vitro)
Preclinical (in vitro)		 Alhayek A, et al. 2022. J Med Chem
N-[2-[4-[(2-acetamidophenoxy)methyl]triazol-1-yl]ethyl]-N'-hydroxy-2-(2-methylpropyl)propanediamide Depiction based on curated SMILES OH N H O H 3 C O NH O CH 3 N N N N H O CH 3 Bacillus
Clostridium		 Collagenase
Collagenase		 Preclinical (in vitro)
Preclinical (in vitro)		 Alhayek A, et al. 2022. J Med Chem
[6-[(3,4-dichlorophenyl)carbamoyl]-3-phosphonoquinoxalin-2-yl]phosphonic acid Depiction based on curated SMILES N HO HO O P OH HO O P N O Cl Cl NH Bacillus
Clostridium		 Collagenase
Collagenase		 Preclinical (in vitro)
Preclinical (in vitro)		 Alhayek A, et al. 2022. J Med Chem
4-[(3-ethoxy-2-hydroxyphenyl)methyl]-N-(4-fluorophenyl)-5-oxo-1,3,4-thiadiazine-2-carboxamide Depiction based on curated SMILES O S F H 3 C NH O N N OH O Chlamydia TTSS (Type III secretion system) Preclinical (in vitro) Zigangirova NA, et al. 2012. Acta Naturae
   


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