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Compound category: Anilides
(total 43 related compounds in database, current show from 21 to 30)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
Compound 11
(internal name in literature)
Depiction based on curated SMILES N HN NH 2 N CH 3 HN O N N H Clostridium Exotoxin; Regulation Preclinical (in vitro) Thanissery R, et al. 2018. Front Microbiol
N-[3-(2-amino-1H-imidazol-5-yl)phenyl]-4-pentylbenzamide;hydrochloride Depiction based on curated SMILES HN ClH H 2 N N H N H 3 C O Escherichia Biofilm Preclinical (in vitro) Bunders CA, et al. 2010. Bioorg Med Chem Lett
N-[4-(2-amino-1H-imidazol-5-yl)phenyl]-3,5-difluorobenzamide;hydrochloride Depiction based on curated SMILES N H ClH F F O H 2 N N H N Escherichia
Pseudomonas
Biofilm
Biofilm
Preclinical (in vitro)
Preclinical (in vitro)
Bunders CA, et al. 2010. Bioorg Med Chem Lett
N-[4-(2-amino-1H-imidazol-5-yl)phenyl]-4-pentylbenzamide;hydrochloride Depiction based on curated SMILES N H ClH H 2 N N H N CH 3 O Escherichia Biofilm Preclinical (in vitro) Bunders CA, et al. 2010. Bioorg Med Chem Lett
N-[4-(2-amino-1H-imidazol-5-yl)phenyl]-3,5-dichlorobenzamide Depiction based on curated SMILES NH 2 Cl Cl O N H N H N Francisella Regulation Preclinical (in vitro) Milton ME, et al. 2017. Mol Microbiol
2-benzyl-5-tert-butyl-N-(4-chlorophenyl)pyrazole-3-carboxamide Depiction based on curated SMILES Cl N H O CH 3 N N H 3 C H 3 C Mycobacterium Motility Preclinical (in vitro) Ouertatani-Sakouhi H, et al. 2017. PLoS One
(4-(4-bromo-3,5-bis(trifluoromethyl)phenylcarbamoyl)phenyl)difluoromethylphosphonic acid Depiction based on curated SMILES HO OH O P F F F F F Br F F F NH O Mycobacterium Exoenzyme Preclinical (in vitro) Rawls KA, et al. 2009. Bioorg Med Chem Lett
N'-(3-chloro-4-cyanophenyl)-N-(4-cyanophenyl)propanediamide Depiction based on curated SMILES N H Cl N N O O HN Pseudomonas Biofilm Preclinical (in vitro) Singh VK, et al. 2022. Nat Commun
N'-(4-bromophenyl)-N-(4-cyanophenyl)propanediamide Depiction based on curated SMILES O Br N H N O NH Pseudomonas Biofilm Preclinical (in vitro) Singh VK, et al. 2022. Nat Commun
N'-(4-chlorophenyl)-N-(4-cyanophenyl)propanediamide Depiction based on curated SMILES O Cl N H N O NH Pseudomonas Biofilm Preclinical (in vitro) Singh VK, et al. 2022. Nat Commun
   


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