Drug details:
Molecular formula: C₁₆H₁₃ClF₂N₄O

Standard name: N-[4-(2-amino-1H-imidazol-5-yl)phenyl]-3,5-difluorobenzamide;hydrochloride

Curated SMILES: C1=CC(=CC=C1C2=CN=C(N2)N)NC(=O)C3=CC(=CC(=C3)F)F.Cl

Evidence for compound's anti-virulence activity:

Escherichia
Related VFcategory: Biofilm
Target: Not determined
Drug effect: Inhibits biofilm formation.
Max phase: Preclinical (in vitro)
Publication:
Bunders CA, et al., 2010. Identification of aryl 2-aminoimidazoles as biofilm inhibitors in Gram-negative bacteria. Bioorg Med Chem Lett 20(12):3797-800.

Pseudomonas
Related VFcategory: Biofilm
Target: Not determined
Drug effect: Inhibits biofilm formation.
Max phase: Preclinical (in vitro)
Publication:
Bunders CA, et al., 2010. Identification of aryl 2-aminoimidazoles as biofilm inhibitors in Gram-negative bacteria. Bioorg Med Chem Lett 20(12):3797-800.